[1]袁秋华,张自强,徐安平,等.羟基磷灰石-壳聚糖复合膜旋涂法制备及表征[J].深圳大学学报理工版,2017,34(No.5(441-550)):451-456.[doi:10.3724/SP.J.1249.2017.05451]
 Yuan Qiuhua,Zhang Ziqiang,Xu Anping,et al.Preparation and characterization of hydroxyapatite-chitosan composite coatings using a spin-coating technique[J].Journal of Shenzhen University Science and Engineering,2017,34(No.5(441-550)):451-456.[doi:10.3724/SP.J.1249.2017.05451]
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羟基磷灰石-壳聚糖复合膜旋涂法制备及表征()
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《深圳大学学报理工版》[ISSN:1000-2618/CN:44-1401/N]

卷:
第34卷
期数:
2017年No.5(441-550)
页码:
451-456
栏目:
化学与化工
出版日期:
2017-09-20

文章信息/Info

Title:
Preparation and characterization of hydroxyapatite-chitosan composite coatings using a spin-coating technique
文章编号:
201705002
作者:
袁秋华张自强徐安平巫剑波秦草坪陈泽汇林松鑫张培新
深圳大学化学与环境工程学院,广东深圳 518060
Author(s):
Yuan Qiuhua Zhang Ziqiang Xu Anping Wu Jianbo Qin Caoping Chen Zehui Lin Songxin and Zhang Peixin
College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, Guangdong Province, P.R.China
关键词:
生物材料学羟基磷灰石壳聚糖复合膜旋涂法力学性能
Keywords:
biomaterials science hydroxyapatite chitosan composite coatings spin-coating technique mechanical property
分类号:
R 318.08
DOI:
10.3724/SP.J.1249.2017.05451
文献标志码:
A
摘要:
为制备高效环保仿生材料,以Na2HPO4和Ca(NO3)2·4H2O为原料,采用化学沉淀法合成羟基磷灰石粉体,将粉体超声分散在壳聚糖醋酸溶液中,通过溶液共混和磁力搅拌的方法制备羟基磷灰石-壳聚糖(hydroxyapatite-chitosan, HA-CS)悬浮液.采用旋涂法在不锈钢304基材表面涂覆HA-CS悬浮液,分别在25 ℃和37 ℃条件下干燥12 h成膜.将两种HA膜样分别通过X射线衍射、傅立叶变换红外光谱、扫描电子显微镜、X射线能量色散仪和电子拉力机进行测试.结果表明,HA-CS复合材料的拉伸强度达(69.04±1.21)MPa;复合膜结晶度好,黏结致密,无分解,无杂质;旋涂法能更好的使HA均匀分散在CS中,减少HA微粒的团聚和游离;与25 ℃相比,37 ℃条件下干燥HA膜有助于HA与CS更多更好地结合,使制得的HA-CS复合膜具有优良性能.为HA-CS复合膜附着金属植入物在人体环境内成功生长提供理论参考.
Abstract:
Based on a chemical precipitation method, the hydroxyapatite powders were prepared using Na2HPO4 and Ca(NO3)2·4H2O as raw materials. The powders were dispersed into chitosan-acetic acid solution with the aid of continuous ultrasonic agitation to prepare hydroxyapatite-chitosan (HA-CS) suspension via solution blending and magnetic stirring. Hydroxyapatite-chitosan composite coatings were fabricated on 304-type stainless steel substrates by a spin-coating technique, then dried at 25 ℃ and 37 ℃ for 12 h, respectively. The two synthesized samples were characterized and tested by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and electronic tensile machine. The results indicate the tensile strength of HA-CS composites reaches up to (69.04±1.21) MPa, and the coatings display good crystallinity, good adhesion, high purity and little decomposition. In addition, by means of spin-coating technique, HA could be evenly dispersed in CS and there are no aggregated or free HA particles in the coatings. The HA-CS composite coatings show better performance when drying at 37 ℃ than at 25 ℃, which is more conducive to combine interaction between HA and CS.

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备注/Memo

备注/Memo:
Received:2016-11-01;Revised:2017-02-27;Accepted:2017-06-08
Foundation:National Nature Science Foundation of China (21471102); Shenzhen Science and Technology Basic Research Foundation (JCYJ20150525092941007)
Corresponding author:Associate professor Yuan Qiuhua. E-mail: yuanqiuh@szu.edu.cn
Citation:Yuan Qiuhua, Zhang Ziqiang, Xu Anping, et al. Preparation and characterization of hydroxyapatite-chitosan composite coatings using a spin-coating technique[J]. Journal of Shenzhen University Science and Engineering, 2017, 34(5): 451-456.(in Chinese)
基金项目:国家自然科学基金资助项目(21471102);深圳市科技基础研究计划资助项目(JCYJ20150525092941007)
作者简介:袁秋华(1967—),男,深圳大学副教授、博士.研究方向:无机仿生材料.E-mail:yuanqiuh@szu.edu.cn
引文:袁秋华,张自强,徐安平,等.羟基磷灰石-壳聚糖复合膜旋涂法制备及表征[J]. 深圳大学学报理工版,2017,34(5):451-456.
更新日期/Last Update: 2017-09-11