[1]袁秋华,张自强,徐安平,等.羟基磷灰石-壳聚糖复合膜旋涂法制备及表征[J].深圳大学学报理工版,2017,34(No.5(441-550)):451-456.
 Yuan Qiuhua,Zhang Ziqiang,Xu Anping,et al.Preparation and characterization of hydroxyapatite-chitosan composite coatings using a spin-coating technique[J].Journal of Shenzhen University Science and Engineering,2017,34(No.5(441-550)):451-456.
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羟基磷灰石-壳聚糖复合膜旋涂法制备及表征()
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《深圳大学学报理工版》[ISSN:1000-2618/CN:44-1401/N]

卷:
第34卷
期数:
2017年No.5(441-550)
页码:
451-456
栏目:
化学与化工
出版日期:
2017-09-30

文章信息/Info

Title:
Preparation and characterization of hydroxyapatite-chitosan composite coatings using a spin-coating technique
作者:
袁秋华张自强徐安平巫剑波秦草坪陈泽汇林松鑫张培新
深圳大学化学与环境工程学院,广东深圳 518060
Author(s):
Yuan Qiuhua Zhang Ziqiang Xu Anping Wu Jianbo Qin Caoping Chen Zehui Lin Songxin and Zhang Peixin
College of Chemistry and Environmental Engineering,Shenzhen University, Shenzhen 518060, Guangdong Province, P.R.China
关键词:
生物材料学羟基磷灰石壳聚糖复合膜旋涂法力学性能
Keywords:
biomaterials science hydroxyapatite chitosan composite coatings spin-coating technique mechanical property
文献标志码:
A
摘要:
为制备高效环保仿生材料,以Na2HPO4和Ca(NO3)2·4H2O为原料,采用化学沉淀法合成羟基磷灰石粉体,将粉体超声分散在壳聚糖醋酸溶液中,通过溶液共混和磁力搅拌的方法制备羟基磷灰石-壳聚糖(hydroxyapatite-chitosan, HA-CS)悬浮液.采用旋涂法在不锈钢304基材表面涂覆HA-CS悬浮液,分别在25 ℃和37 ℃条件下干燥12 h成膜.将两种HA膜样分别通过X射线衍射、傅立叶变换红外光谱、扫描电子显微镜、X射线能量色散仪和电子拉力机进行测试.结果表明,HA-CS复合材料的拉伸强度达(69.04±1.21)MPa;复合膜结晶度好,黏结致密,无分解,无杂质;旋涂法能更好的使HA均匀分散在CS中,减少HA微粒的团聚和游离;与25 ℃相比,37 ℃条件下干燥HA膜有助于HA与CS更多更好地结合,使制得的HA-CS复合膜具有优良性能.为HA-CS复合膜附着金属植入物在人体环境内成功生长提供理论参考.
Abstract:
Based on a chemical precipitation method, the hydroxyapatite powders were prepared using Na2HPO4 and Ca(NO3)2·4H2O as raw materials. The powders were dispersed into chitosan-acetic acid solution with the aid of continuous ultrasonic agitation to prepare hydroxyapatite-chitosan (HA-CS) suspension via solution blending and magnetic stirring. Hydroxyapatite-chitosan composite coatings were fabricated on 304-type stainless steel substrates by a spin-coating technique, then dried at 25 ℃ and 37 ℃ for 12 h respectively. The two synthesized samples were characterized and tested by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and electronic tensile machine. The results indicate the tensile strength of HA-CS composites reaches up to (69.04±1.21) MPa, and the coatings display good crystallinity, good adhesion, high purity and little decomposition. In addition, by means of spin-coating technique, HA could be evenly dispersed in CS and there are no aggregated or free HA particles in the coatings. The HA-CS composite coatings show better performance when drying at 37 ℃ than at 25 ℃, which is more conducive to combine interaction between HA and CS.

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更新日期/Last Update: 2017-09-11